Monoclonal Antibody Infusions for COVID-19

Cumberland Emergency Medical Services (EMS) is now providing in-home monoclonal antibody infusions for individuals who test positive for COVID-19, are age 12 or older, have mild to moderate symptoms within last 10 days of a positive test, and are at high risk for progressing to severe disease.   Conditions that place an individual at high risk for disease progression include, but are not limited to obesity, heart disease, hypertension, kidney disease, asthma, chronic obstructive pulmonary disease, diabetes, immunosuppressive diseases, or the use of immunosuppressive medications.    Other conditions may also increase someone’s risk and people should check with their medical provider. 
 

A monoclonal antibody is a laboratory-produced protein that functions like the antibodies made by the body in response to infection.  By binding to a specific molecule on the SARS-CoV2 virus known as an antigen, the administration of monoclonal antibodies can enhance or restore the immune response against the virus.    Patients with COVID-19 who receive monoclonal antibodies generally have milder symptoms and are less likely to require hospitalization.  The administration of monoclonal antibodies can cut the risk of hospitalization and death if given early enough after testing positive.  Most patients begin to feel noticeably better within 24 hours of receiving their infusion.    Monoclonal antibodies are administered by intravenous infusion.    Patients who have received an infusion will be monitored for an hour after receiving the infusion. 
 

Individuals diagnosed with COVID-19 should reach out to their medical provider to determine if they are a candidate to receive monoclonal antibodies.  A referral form can be found at here. Once the form is completed by a medical provider, the form should be faxed to 401-334-3113 or emailed to ems@cumberlandri.org.   The medical provider or patient should call 401-334-3090 extension 6 to confirm receipt of the referral form.   Patients and medical providers may call 401-334-3090 extension 6 with any questions regarding in-home monoclonal antibody infusions.